What We Do
The Issues
ONE prioritizes our support for the investments that have the greatest impact on the areas with the largest need, with a focus on resilience and self-sufficiency. This is why we focus on Africa. Africa is young and vibrant – the fastest growing continent on the planet, providing new markets, export opportunities, and jobs in the US.
The latest
US-Africa Trade: An Unfinished Story
Africa is the fastest-growing region in the world but the US is falling behind. Why? Read ONE’s latest report to learn more.
Survey Finds Rising Support for Global Disease Funding in 2026
New nationwide polling from ONE shows strong and growing public support for US global health funding and disease prevention efforts abroad.
Amb. Mark A. Green on Domestic Resource Mobilization, Innovative Financing, and Global Health
In remarks delivered on Capitol Hill, Green urged policymakers to expand support for domestic resource mobilization, innovative financing, and country-led development strategies.
Want to learn more? Click on a topic below to explore.
Foreign Assistance
Smart, strategic foreign assistance enables countries to be self-reliant, with healthy populations that power healthy economies.
FY 2027 Presidential Budget Request: Overview & Key Highlights
Everything you need to know about how the budget request impacts US foreign assistance.
FY2026 NSRP Appropriations & Oversight Tracker
Explore ONE’s FY2026 NSRP appropriations spreadsheet, compiling key consultation, notification, and reporting requirements into one centralized location.
‘Soft power’: Americans debate US foreign aid cuts
Frank Luntz asks Americans to share their opinions, questions and concerns regarding recent cuts to US foreign assistance.
Global Health
US investments have bolstered health systems in low- and middle-income countries, ensuring they are better equipped to handle health crises and deliver health services on their own.
Poll: Americans Broadly Support Investments in International Health
A recent survey showed broad bipartisan support for these efforts.
US Investment in the Global Fund Strengthens the US Economy
Learn about how this program provides a return on investment for US businesses.
Effective Implementation of the America First Global Health Strategy
The strategy centers on keeping America safer, stronger, and more prosperous, while strengthening global health security and country ownership over health financing.
Economic Development
Creating economic opportunities is critical to fostering this development and lifting communities out of poverty.
The African Growth and Opportunity Act (AGOA)
Learn about how AGOA has been the foundation of U.S. trade and economic relationships with Africa, unlocking key African markets for U.S. companies, allowing them to diversify supply chains and better compete globally.
A Prosperous Partnership for America: The African Development Fund
The ADF is one of the most effective vehicles for America’s investments to promote self-reliance and growth. This helps create stable countries that are stronger and more prosperous partners for the U.S.
G7 Share of Aid to Africa at 50-year Low
Despite immense need for investments to tackle economic, health, and climate crises, G7 & EU look inward.