What We Do
The Issues
ONE prioritizes our support for the investments that have the greatest impact on the areas with the largest need, with a focus on resilience and self-sufficiency. This is why we focus on Africa. Africa is young and vibrant – the fastest growing continent on the planet, providing new markets, export opportunities, and jobs in the US.
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Foreign Assistance
Smart, strategic foreign assistance enables countries to be self-reliant, with healthy populations that power healthy economies.

Economic Development
Creating economic opportunities is critical to fostering this development and lifting communities out of poverty.

Global Health
US investments have bolstered health systems in low- and middle-income countries, ensuring they are better equipped to handle health crises and deliver health services on their own.

119th Congress Briefing Book
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Our Impact
Here’s a look at what our activists have achieved by using their voice to demand change.

Our Model for Change
Learn how we work to ensure everyone, everywhere can lead a life of dignity and opportunity.

Get Involved
Check out our current actions and more ways you can get involved now.

Stories, Insights & Perspectives
Read the latest on how your activism can fight for justice and equality.