Johannesburg, South Africa – November 21, 2025 – Following the 8th Replenishment of the Global Fund to Fight AIDS, Tuberculosis and Malaria, Ndidi Okonkwo Nwuneli, CEO of the ONE Campaign, issued the following statement:  

“While today’s pledges fell short of the US$18 billion total fundraising target, it is clear many world leaders still chose to prioritize lifesaving health investments. 

“In a world where progress is fragile and the most vulnerable bear the heaviest burden, we need leaders to step up and support life-saving programs like the Global Fund. We have the innovations required to tackle these deadly diseases and create healthy lives for everyone – we just need the resources and political will to end them in our lifetime. 

“We cannot stop. Now is the time to invest in proven solutions.” 

Adrian Lovett, Executive Director for the UK, Middle East and Asia Pacific at the ONE Campaign, speaking from the 8th Global Fund Replenishment event in Johannesburg said: 
 
“This first ever global health replenishment on African soil has been convened with resolve and purpose – a reminder of what determined leadership looks like in the fight against AIDS, TB and malaria. 

“But today’s outcome also exposes a worrying reality. Just as the world stands on the brink of an incredible breakthrough in reducing deaths from these devastating diseases, some partners have stepped back from the fight. At the last replenishment, nearly 90% of the funds pledged came from seven leading donors. This time, four of those reduced their pledge and three – France, Japan and the European Commission – did not pledge today, though they have promised to in the future. We urge them to do so.  

“Today represents a vital step forward, but governments must go further to top up their pledges and finish the job. Millions of lives depend on leaders matching their words with action.” 

To track ongoing progress towards the Replenishment of the Global Fund, visit ONE Data: https://data.one.org/analysis/global-fund-8th-replenishment-tracker 

Since 2002, the Global Fund has saved 70 million lives and helped cut deaths from AIDS, tuberculosis and malaria by 63% – a public health achievement that has transformed communities and given millions the chance to thrive. The 8th Replenishment targets US$18 billion to continue its work uniting the world to find solutions and scale them. This strategic investment would save 23 million lives between 2027 and 2029 and prevent around 400 million infections.

Our world is safer, more prosperous and more stable when we work together to combat disease. Today’s replenishment conference demonstrates that, even in these turbulent times, there still exists a spirit of international cooperation to defeat these terrible diseases. But we need to continue investing. 
 

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Source: The Global Fund to Fight AIDS, Tuberculosis and Malaria https://www.theglobalfund.org/en/investment-case

About ONE: 
 

ONE is a global, nonpartisan organization advocating for the investments needed to create economic opportunities and healthier lives in Africa. Since 2004, we have helped secure more than $1 trillion in new investments that build a safer, more prosperous world. Our trusted advocacy combines hard-hitting data, grassroots activism and political engagement to influence decision-makers and drive lasting change. Learn more at ONE.org