Gayle E. Smith is CEO of the ONE Campaign. She has served as a top advisor on international issues for three American presidents and is one of the world’s leading experts on global development and global health security. She brings an unparalleled expertise and an extraordinary network of relationships across the African continent and around the world. In 2021, Smith took on a temporary role at the request of the Secretary of State and served as US State Department’s Coordinator for Global COVID Response & Health Security, where she played a leading role in the US effort to end the global pandemic.
Prior to joining the ONE Campaign, Smith served as the Administrator of the United States Agency for International Development, where she led a staff of more than 10,000 people working to end extreme poverty, foster sustained and inclusive economic growth, and promote resilient, democratic societies all over the world. Smith had previously served as Special Assistant to President Obama and Senior Director for Development and Democracy at the National Security Council, where she played a lead role in the response to the Ebola epidemic and presidential development initiatives including Power Africa and Feed the Future. Before her work at the NSC during the Obama Administration, Smith founded the Sustainable Security Program at the Center for American Progress and co-founded the ENOUGH project and the Modernizing Foreign Assistance Network. She served as Special Assistant to President Clinton and Senior Director for African Affairs at the NSC in the late 1990s, and prior to that lived and worked in Africa for 20 years, working as a journalist and with NGOs. Smith is originally from Bexley, Ohio and earned a B.A. from the University of Colorado. Smith also won first place in the standing long jump in elementary school.
* Also serves on the ONE Action Board.
Director and Professor, School of Transnational Governance, European University Institute
President/Chief Executive of the Dangote Industries LTD and Chairman of the Dangote Foundation
Co-founder, ONE and (RED)
Lead singer, U2
Co-founder, ONE and (RED)
Former Prime Minister of the United Kingdom
Chief Executive Officer, African Leadership Institute
Chairman, Mo Ibrahim Foundation
President & CEO, Chicago Community Trust *
Co-Founder, ONE & Sharing Strategies
Managing Director, Global Policy & Advocacy, Europe, Middle East & East Asia, Bill & Melinda Gates Foundation
Chairman, Kleiner Perkins
CEO, Business Roundtable *
Former United States Senator
Global Head of External Relations, Bloomberg L.P
Former Secretary of the Treasury of the United States
Senior Vice President for Public-Private Partnerships, Mastercard Inc.
Senior Advisor, Open Society Foundations *
Chief Operating Officer of Meta and Founder of Lean IN
Chairwoman, The Sherwood Foundation and the Susan Thompson Buffett Foundation
Board Chair, ONE, and Principal, Firefly3 *
* also serves on the ONE Action Board.