Today is World Tuberculosis Day.

Last week, the WHO released it’s newest study on the disease, reporting that while TB cases have been slowly falling since 2003, a drug-resistant strain of TB (MDR-TB) is on a steep rise. Worldwide we can expect about 9 million new cases of TB this year, and 500,000 new cases of MDR-TB.

Learn more at the World TB Day site.

And scroll though the ONE Blog’s “TB” tag for our recent postings.

Including:

• Alexandra Fullem’s (of the the Global Health Council) excellent account of the Congressional briefing in honor of World TB Day on the 13th and the status of TB overall.
• A summary of the WHO’s February report on TB and MDR-TB
• A LA Times editorial urging world leaders for more funding to fight the drug-resistant strain of TB.

And more.

(Alexandra Fullem works for the Global Health Council)

Yesterday the Global Health Council, Aeras Global TB Vaccine Foundation and the American Thoracic Society hosted a Congressional briefing in honor of World TB Day 2008. We learned from our 3 speakers more about the threat of MDR and XDR TB, more about the perfect storm of TB/HIV co-infection and about the great work that is being done in the push to find a vaccine. The speakers were Dr. Payam Nahid from the University of California, San Francisco, Thomas Kenyon from the Office of the Global AIDS Coordinator and Sylvie Kwedie from the Aeras Global TB Vaccine Foundation.

So, why is TB, an ancient disease, continuing to plague us after 5000 years? There are many reasons and the speakers outlined these for us. The first is poverty. The disease spreads quickly through the air and so we are all at risk, but those living in poverty even more so. The second is the rise of the HIV/AIDS epidemic. 1/3 of the population is carrying a latent form of TB. Once your immune system is compromised it becomes much more likely you will progress to active TB. In fact, TB is the leading cause of death for HIV patients with up to 40% of HIV deaths being TB related. The third reason that TB is still with us is poor TB control programs worldwide and poor laboratory capabilities, especially in endemic countries.

A fourth reason is that the drugs we are using to treat TB all date from the 1940’s, 50’s and 60’s.We are treating this disease with very old technology.

This, together with (more…)