Blog Contributor:

Rena Pacheco-Theard

ayuba-provides-wheelchairs-and-hope-for-polio-victims

Over 5 Million People on HIV Treatment


over-5-million-people-on-hiv-treatment

Jul 19th, 2010 5:08 PM UTC
By Rena Pacheco-Theard

It was just announced today at the International AIDS Conference in Vienna that an estimated 5.2 million people globally were on life-saving antiretroviral treatment for HIV at the end of 2009. This latest estimate from the WHO represents an additional 1.2 million people on treatment compared to the number in 2008. Increased leadership and resources in the fight against HIV/AIDS have helped to increase the number of people on treatment 12-fold since 2003.

Dr Hiroki Nakatani, WHO Assistant Director-General for HIV, Tuberculosis, Malaria and Neglected Tropical Diseases said, “This is the largest increase in people accessing treatment in a single year. It is an extremely encouraging development.”

Check back for further analysis at the conclusion of the XVIII International AIDS Conference.

Debt Swap Agreement Will Help Indonesia Fight Tuberculosis


debt-swap-agreement-will-help-indonesia-fight-tuberculosis

Jul 16th, 2010 9:39 AM UTC
By Rena Pacheco-Theard

Officials from Australia, Indonesia and the Global Fund just announced an agreement that will boost support to Indonesia’s tuberculosis control programs.

The Debt2Health agreement helps redirect money from servicing debt to improving public health. Australia will cancel AUD$75 million of Indonesia’s debt and Indonesia will put half of this amount into national programs to fight tuberculosis through the Global Fund. These additional resources will be particularly useful as Indonesia has the world’s third highest rate of tuberculosis.

Executive Director of the Global Fund, Michel Kazatchkine commended this Debt2Health agreement, saying:

In order to reach and sustain the level of funding we need in the fight against the most deadly epidemics of our time, we must make use of innovative financing opportunities like Debt2Health. We are delighted that Australia has joined the initiative and are very grateful for the trust that it shows in our work.

Over the years, ONE has worked on ensuring debt relief for the poorest countries and finding innovative sources of financing for health, so it is very good news indeed to see them coming together in this Debt2Health agreement for the benefit of Indonesians.

Progress on Polio in Nigeria


progress-on-polio-in-nigeria

Jul 14th, 2010 11:17 AM UTC
By Rena Pacheco-Theard

Last week, the Centers for Disease Control and Prevention’s Morbidity and Mortality Weekly Report included promising information on a significant drop in polio cases in Nigeria. One of four remaining polio-endemic countries, Nigeria had the highest number of polio cases anywhere in the world (an estimated 798) in 2008. In 2009, the number was more than halved to 388, and from January through June of this year only three cases have been reported, representing an all-time low and a more than 99 percent reduction in cases.

Previously, Nigeria had been plagued by a high proportion of under- and unimmunized children that led the country to be a source of continued international wild polio transmission (WPV). A reenergized eradication campaign that increased pressure for vaccines helped to turn to the tide. The CDC’s report also credits the drop in cases to the increased involvement of traditional, religious and political leaders in promoting vaccination and generating acceptance within communities.

In an April Wall Street Journal article, Gates Rethinks His War on Polio, Bill Gates noted that a recalibrated campaign was needed to fight polio and improve the overall health of those in developing countries. This article referenced an earlier trip Gates took to Nigeria, where he called attention to the importance of local leaders as allies in polio eradication efforts.

Improved poliovirus surveillance and immediate immunization responses to new cases will be critical elements to continue to halt transmission. The coming months, July through September, represent a traditionally high polio transmission season. If progress can be sustained, Nigeria stands to significantly disrupt the spread of WPV.

An Inside Look at TB Vaccine Development


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Jul 13th, 2010 1:22 PM UTC
By Rena Pacheco-Theard

Tour of Aeras TB Vaccine Facility 070610 021

Last week, my colleagues Erin, Margaret and I (that’s us in the lab coats) went on a tour of the Aeras Global TB Vaccine facility in Rockville, Maryland. We were there to learn more about the need for a new tuberculosis (TB) vaccine and to see how the vaccine development process works.

A new vaccine for TB is urgently needed. Every year, more than 9.4 million people become sick with TB and about 1.8 million people die from the disease, including 0.5 million people who are also HIV-positive. The existing BCG vaccine was first used in 1921, does not always protect people from getting TB, and is not safe for those with weakened immune systems, such as those living with HIV (a significant shortcoming as TB is the leading cause of death among persons infected with HIV in Africa). Our Aeras guides stressed the important of addressing TB in order to protect the historic progress achieved through recent investments in HIV/AIDS.

Tour of Aeras TB Vaccine Facility 070610 026

The Aeras Global TB Vaccine Foundation is a non-profit product development partnership dedicated to the development of safe and effective TB vaccine regimens that will prevent tuberculosis in all age groups and will be affordable, available and adopted worldwide. Our tour of the Aeras Global TB Vaccine facility involved a look at the following steps of TB vaccine development: vaccine discovery, molecular biology, process development, cell banks, manufacturing: shake flasks and 20 liter seed fermenter, manufacturing: 200 liter fermenter, manufacturing: harvest, quality control, spray drying for aerosol vaccines, and fill and finish. We also learned about the steps that come later, including shipping bulk product to manufacturing partners and delivery.

That’s just an overview, and if it sounds complicated, that’s because it is. Aeras scientists are well-trained and committed to developing safe and effective TB vaccine regimens, but vaccine development is a lengthy process and Aeras estimates that we are about ten years away from a vaccine that that has been thoroughly tested and can be delivered around the world. Aeras has four vaccine candidates currently in clinical trials in Africa, Europe and the U.S.

If you’d like to learn more about the great work the Aeras Global TB Vaccine Foundation is doing, you can visit their website at www.aeras.org.

Videos Show Need and Plan for Action on Polio


videos-show-need-and-plan-for-action-on-polio

Jun 23rd, 2010 9:57 AM UTC
By Rena Pacheco-Theard

Check out these great videos from the WHO that movingly display the need to move to 100% polio eradication, and the plan that was launched to do just that:

Countries Selected for Additional U.S. Global Health Support


countries-selected-for-additional-u-s-global-health-support

Jun 18th, 2010 6:57 PM UTC
By Rena Pacheco-Theard

This morning, the State Department, USAID and the Department of Health and Human Services released a joint press release announcing the first round of “GHI Plus” countries, and providing details on the program’s governance. As we have described before, the U.S. Global Health Initiative (GHI) is a $63 billion initiative to coordinate and expand U.S. efforts to improve global health over six years.

While GHI activities are ongoing in over 80 countries where the U.S. is already working, today eight countries were selected to receive additional technical and management resources: Bangladesh, Ethiopia, Guatemala, Kenya, Malawi, Mali, Nepal and Rwanda. As the Wall Street Journal writes, these “GHI Plus” countries will serve as “learning labs for a new global health strategy aimed in part at reducing maternal and child deaths and combating preventable disease.”

Mirroring its inclusive approach to improving global health, the GHI is led by an Operations Committee that includes support from across the government, including Dr. Rajiv Shah, Administrator, U.S. Agency for International Development; Ambassador Eric Goosby, U.S. Global AIDS Coordinator, U.S. Department of State; and Dr. Thomas Frieden, Director, Centers for Disease Control and Prevention, Department of Health and Human Services. The Operations Committee works in close coordination with Deputy Secretary of State Jacob J. Lew, and high-level support on the GHI comes from the GHI Strategic Council, which includes representatives from a range of U.S. agencies that have expertise in areas critical to the GHI.

Ayuba Provides Wheelchairs and Hope for Polio Victims


ayuba-provides-wheelchairs-and-hope-for-polio-victims

Jun 18th, 2010 5:55 PM UTC
By Rena Pacheco-Theard

Ayuba Gufwan is a polio survivor and the Executive Director of Wheelchairs for Nigeria and the Beautiful Gate Initiative. He is in Geneva today to help formally launch the new 2010-2012 Strategic Plan for eradicating polio. I had the pleasure of asking Ayuba a few questions about his experience with polio and how he is working to improve the lives of other polio victims.

How old were you when you got polio?

I had polio at the age of 4. I was getting ready to celebrate my fifth birthday. I remember when I was very small — when I used to use my two legs — but that was only a very short experience.

What do you remember about those first few years with polio?

I was very frustrated. I remember one time in my village, which is in a rural part of Nigeria — when you grow up in a rural area, your childhood and teenage years are characterized by adventures.

I was very outspoken with my peers and I used to come up with a million suggestions like, “Let’s do this. Let’s go here.” I had all sorts of ideas, but when it came to the implementation of those ideas I was limited by mobility. And normally my friends would say, “Well, you stay here while we go into the bush and hunt for the food and we’ll come back for you when we find something.” But in most cases they never came. But if I insisted on going with them I’d have to go on the ground and it would take the whole day and they would never get there in time for what they wanted to do. So, they devised a plan. They would say, “Ready . . . one, two, three . . .” and then they would take off running and I was left there and I was really, really frustrated. Sometimes I would just break down and start crying and crawl back home very slowly and very sadly. I was really bitter growing up because of the effects of polio.

In fact, polio made it impossible for you to attend school?

It was very difficult. You know one effect of polio for me as a child was that I developed an inferiority complex. My parents saw polio as the end of my life. In fact my name is “Burki.” And “burki” means to apply the brakes. My father’s friend was the one that gave me the name. What that meant, according to my parents was, “This boy would’ve amounted to something great in life, but this polio has put the brakes on his progress in life.” And so, he didn’t want me to go to school.

How did your life change when you got your first wheelchair?

So, when I got a bicycle wheelchair at the age of 19 I started going back to school. Then I had my hope, dignity, and self-worth restored. And it was then that I started overcoming the inferiority complex that had developed in me because of polio.

That wheelchair was the turning point in my life.

I felt as if my legs had been restored. I felt that all of my obstacles came tumbling down. I was able to move from one point to another comfortably and that changed my life. I remember that day very, very well. It was on the 14th of April and the events of that day are still evergreen in my memory. That was a wonderful day.

And that is part of the reason I am moved to do what I do now with Wheelchairs For Nigeria; because I know that if you’ve come down with polio or any other crippling disease that the wheelchair can actually restore your hope and turn around your life.

Instead of practicing law, you decided to make wheelchairs for polio survivors. What made you choose that direction?

As a small boy I always dreamed of becoming a lawyer, but it was hard for me because I didn’t get to go directly to the university. I went to a college of education and took a teaching appointment. I came back to the faculty of the University of Jos for five years, and as soon as I graduated I started thinking about myself and what career I should take.

I knew law could give me money and give me fame, but I was wondering, “What about the hundreds and hundreds of kids who have polio? What can I do to help them?” So I put my ambition for the law aside and decided to give my time, my energy, and my strength to working with the thousands of polio survivors.

What do the recipients of your custom wheelchairs say to you?

Oh my goodness. When I give someone a wheelchair, and I look straight in a person’s eyes, I see the joy and the restoration of hope. As soon as you pick up a child and place them down in a wheel chair they break down into tears of joy. It really touches me. And I say, let’s get on to the next child!

Almost everyone has the same feeling I have when I got my wheelchair. When you live the remotest part of Nigeria like I do you can’t get around unless someone volunteers to carry you on the shoulders.

Over the last ten years we’ve given away over 3,000 wheelchairs. The people who have received the wheelchairs have gone back to school, they’ve learned a trade.

How are you and other polio survivors spreading the message of immunization?

When we meet with people I raise their awareness about polio immunization and ask them to spread the word. There’s been tremendous effort. People are doing this in their communities, in their churches, wherever people are gathered. There are so many people who are taking the initiative and they are doing an excellent job in reaching out to people.

What message would you like to share with the world about polio eradication?

I would plead with the world community to sustain the tempo so that polio can finally be eradicated.

Growing up in my village we had an adventurous lifestyle. A part of that adventure was going to hunt for birds with our slingshots. Sometimes we would aim at a bird and shoot and miss. We’d say, “Oh! I nearly got it!” And the tendency is to want to celebrate because you nearly got the bird. An elder friend of ours said, “Nearly does not kill the bird. You have to hit the bird and that is when you should celebrate.” When it comes to polio eradication, if the global community stops today because we have done 99% and they say, “We deserve an A,” that doesn’t end the matter. We have to get 100%. If we all stop today, polio will roll back and we’ll go backwards. We’ll lose all of our achievement. So, when it comes to polio, “Nearly does not kill the bird.”

We have to say we eradicated polio . . . not that we almost eradicated polio.

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